Microvascular mechanisms of age‐related cognitive decline (1082.1)
نویسندگان
چکیده
منابع مشابه
Mechanisms of late-onset cognitive decline after early-life stress.
Progressive cognitive deficits that emerge with aging are a result of complex interactions of genetic and environmental factors. Whereas much has been learned about the genetic underpinnings of these disorders, the nature of "acquired" contributing factors, and the mechanisms by which they promote progressive learning and memory dysfunction, remain largely unknown. Here, we demonstrate that a p...
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White Matter Disease is increasingly being recognized as an important cause of cognitive decline and dementia. Various investigations have linked chronic diet-related conditions to the development of white matter lesions, which appear as white matter hyperintensities on T2-weighted magnetic resonance imaging (MRI) scans of the brain. Thus, it can be postulated that the metabolic, inflammatory, ...
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Andrea Talesa,∗, Frank Jessenb,c, Christopher Butlerd, Gordon Wilcockd, Judith Phillipse and Tony Bayerf aCollege of Human and Health Sciences, Department of Psychology, Swansea University, Swansea, Wales, UK bDepartment of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany cGerman Center for Neurodegenerative Disorders (DZNE), Germany dNuffield Department of Clinical Neurosci...
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INTRODUCTION Age-associated cognitive decline-or normal (non-pathological, normative, usual) cognitive ageing-is an important human experience which differs in extent between individuals. The determinants of the differences in age-related cognitive decline are not fully understood. Progress in the field is taking place across many areas of biomedical and psychosocial sciences. AREAS OF AGREEM...
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Stroke and cognitive impairment are common among older persons.1 It is estimated that the lifetime risk for stroke is approximately 1 in 5 for women and 1 in 6 for men,2 and almost one-third of persons with stroke, which typically may involve motor, sensory, or other deficits, may have a significant degree of cognitive impairment within several months of the event.1 Furthermore, silent strokes ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2014
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.28.1_supplement.1082.1